Semaglutide

Person holding a thermometer and showing loose jeans on their waist.

Semaglutide Customer Information

IOverview

Semaglutide is a GLP-1 receptor agonist originally developed for managing type 2 diabetes. It has since gained popularity for its powerful weight loss effects and overall metabolic benefits. It mimics the action of the natural hormone GLP-1, which helps regulate blood sugar, appetite, and digestion.

How Semaglutide Works

  • Mimics GLP-1 hormone to regulate blood sugar and appetite.

  • Slows gastric emptying, helping you feel full longer.

  • Stimulates insulin secretion and suppresses glucagon release.

  • Acts on the brain to reduce hunger and cravings.

  • Improves insulin sensitivity, aiding fat loss and metabolic health.

Key Benefits

✅ Weight Loss

  • Reduces appetite and food intake.

  • Promotes fat burning and long-term weight management.

  • Helps break cycles of emotional or compulsive eating.

✅ Blood Sugar Control

  • Lowers blood glucose levels without causing hypoglycemia.

  • Improves beta-cell function in the pancreas.

✅ Cardiovascular Health

  • Reduces risk of heart attack, stroke, and cardiovascular death.

  • Improves blood pressure and cholesterol levels.

✅ Anti-Inflammatory Effects

  • Reduces systemic inflammation.

  • May benefit conditions like fatty liver disease and metabolic syndrome.

✅ Neuroprotective Potential

  • Early research suggests benefits for Alzheimer’s and Parkinson’s.

  • May reduce neuroinflammation and improve cognitive function.

✅ Behavioral Health

  • May help reduce alcohol consumption and compulsive behaviors.

Dosing Protocols

Option 1: Longevity / General Health

  • Starting dose: 0.25 mg weekly

  • Injection site: Subcutaneous fat (abdomen, thigh, upper arm)

  • Time of day: Flexible

Option 2: Weight Loss Protocol

  • Start low: 0.25 mg weekly

  • Increase gradually: Every 2–4 weeks based on tolerance

  • Typical range: 0.125 mg to 2.4 mg weekly or bi-weekly

Tips to Reduce Side Effects

  • Start with a low dose and increase slowly.

  • Split doses if needed to improve tolerance.

  • Take before meals to reduce nausea.

  • Stay hydrated and eat high-protein, smaller meals.

  • Consider adding vitamins or other peptides for support.

Possible Side Effects

  • Nausea, vomiting, diarrhea, constipation

  • Decreased appetite

  • Fatigue or dizziness

  • Injection site reactions

Contraindications

Do not use Semaglutide if you have:

  • A history of pancreatitis

  • Pregnancy or breastfeeding

  • Severe gastrointestinal disease (e.g., gastroparesis)

  • Personal or family history of medullary thyroid carcinoma

  • Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2)

Conclusion

Semaglutide is a powerful tool for improving metabolic health, managing weight, and reducing the risk of chronic diseases. When used responsibly and under guidance, it offers transformative benefits for many individuals.