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TIRZEPATIDE (MJ) 20MG PEN
Tirzepatide (Mounjaro®) – Dual-Action Weight Loss Injection
Tirzepatide, marketed under the brand name Mounjaro®, is a revolutionary once-weekly injectable medication designed to support significant weight loss, improve metabolic health, and enhance overall well-being. Originally developed for type 2 diabetes management, Tirzepatide is now widely prescribed off-label for weight loss due to its dual-action mechanism and superior results compared to other GLP-1 medications like Semaglutide (Ozempic®) and Liraglutide (Saxenda®). [drugs.com]
How Tirzepatide Works
Tirzepatide is the first and only dual GIP and GLP-1 receptor agonist, often referred to as a “twincretin.” It mimics two natural gut hormones:
GIP (Glucose-Dependent Insulinotropic Polypeptide): Enhances insulin secretion and improves fat metabolism.
GLP-1 (Glucagon-Like Peptide-1): Reduces appetite, slows gastric emptying, and lowers blood sugar levels.
Together, these hormones help:
Suppress appetite and cravings
Increase feelings of fullness
Improve insulin sensitivity
Promote fat loss while preserving lean muscle mass. [goodrx.com]
Clinically Proven Weight Loss Results
In clinical trials, patients using Tirzepatide experienced:
Average weight loss of up to 22% of body weight over 72 weeks
Waist circumference reduction of over 7 inches
Improved metabolic markers, including blood pressure, cholesterol, and blood sugar levels. [drugs.com]
Compared to Semaglutide, Tirzepatide delivered 47% greater weight loss, making it a top choice for individuals seeking transformative results.
Dosage & Administration
Starting dose: 2.5 mg once weekly for 4 weeks (to minimize side effects)
Titration: Increase by 2.5 mg every 4 weeks as tolerated
Maintenance dose: Up to 15 mg weekly, based on individual response
Tirzepatide is administered via a pre-filled, easy-to-use injection pen. It can be self-injected subcutaneously in the abdomen, thigh, or upper arm. Always follow your healthcare provider’s instructions for safe use. [drugs.com]
Common Side Effects
Most side effects are mild and temporary, especially during dose escalation. These may include:
Nausea (13–24%)
Diarrhea (13–21%)
Constipation (6–17%)
Fatigue
Injection site reactions
Serious but rare risks include:
Pancreatitis
Gallbladder issues
Thyroid C-cell tumors (contraindicated in those with a personal/family history of medullary thyroid carcinoma or MEN 2 syndrome). [drugs.com]
Who Should Consider Tirzepatide?
Tirzepatide may be suitable for adults who:
Struggle with obesity or overweight (BMI ≥27 with comorbidities or ≥30)
Have plateaued with diet and exercise alone
Are seeking non-surgical weight loss solutions
Want to improve blood sugar control, energy levels, and overall health
Tirzepatide (Mounjaro®) – Dual-Action Weight Loss Injection
Tirzepatide, marketed under the brand name Mounjaro®, is a revolutionary once-weekly injectable medication designed to support significant weight loss, improve metabolic health, and enhance overall well-being. Originally developed for type 2 diabetes management, Tirzepatide is now widely prescribed off-label for weight loss due to its dual-action mechanism and superior results compared to other GLP-1 medications like Semaglutide (Ozempic®) and Liraglutide (Saxenda®). [drugs.com]
How Tirzepatide Works
Tirzepatide is the first and only dual GIP and GLP-1 receptor agonist, often referred to as a “twincretin.” It mimics two natural gut hormones:
GIP (Glucose-Dependent Insulinotropic Polypeptide): Enhances insulin secretion and improves fat metabolism.
GLP-1 (Glucagon-Like Peptide-1): Reduces appetite, slows gastric emptying, and lowers blood sugar levels.
Together, these hormones help:
Suppress appetite and cravings
Increase feelings of fullness
Improve insulin sensitivity
Promote fat loss while preserving lean muscle mass. [goodrx.com]
Clinically Proven Weight Loss Results
In clinical trials, patients using Tirzepatide experienced:
Average weight loss of up to 22% of body weight over 72 weeks
Waist circumference reduction of over 7 inches
Improved metabolic markers, including blood pressure, cholesterol, and blood sugar levels. [drugs.com]
Compared to Semaglutide, Tirzepatide delivered 47% greater weight loss, making it a top choice for individuals seeking transformative results.
Dosage & Administration
Starting dose: 2.5 mg once weekly for 4 weeks (to minimize side effects)
Titration: Increase by 2.5 mg every 4 weeks as tolerated
Maintenance dose: Up to 15 mg weekly, based on individual response
Tirzepatide is administered via a pre-filled, easy-to-use injection pen. It can be self-injected subcutaneously in the abdomen, thigh, or upper arm. Always follow your healthcare provider’s instructions for safe use. [drugs.com]
Common Side Effects
Most side effects are mild and temporary, especially during dose escalation. These may include:
Nausea (13–24%)
Diarrhea (13–21%)
Constipation (6–17%)
Fatigue
Injection site reactions
Serious but rare risks include:
Pancreatitis
Gallbladder issues
Thyroid C-cell tumors (contraindicated in those with a personal/family history of medullary thyroid carcinoma or MEN 2 syndrome). [drugs.com]
Who Should Consider Tirzepatide?
Tirzepatide may be suitable for adults who:
Struggle with obesity or overweight (BMI ≥27 with comorbidities or ≥30)
Have plateaued with diet and exercise alone
Are seeking non-surgical weight loss solutions
Want to improve blood sugar control, energy levels, and overall health